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SELECT 
  1 
FROM 
  csscart_lock_keys 
WHERE 
  key_id = '7654694922c11b5b39fedc3edd5ee5a705391edf00e4dfc9c712624f3f765dfc' 
  AND token = 'UUIFHMPAofm0novwjWnvh0fYSF5NSztnMONXPUuZI9g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}