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SELECT 
  1 
FROM 
  csscart_lock_keys 
WHERE 
  key_id = 'e015dbb4ab9d237d36b56e610a56eae6eaedaf7222b97c338f53ed6990dd3345' 
  AND token = 'HJtCEi6jB0pSJnBIYoxDGOmD2FKYZR7CM+0sBFOXbzo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}